The Metabolic Link
The Metabolic Link
Latest Episodes
Inflammation and Glycation: The Two Heads of Chronic Disease | Dr. Paul Reynolds, PhD | The Metabolic Link Ep. 96
Dr. Paul Reynolds has spent his career studying what he calls “two heads of the same beast”: inflammation and glycation — two interlocking processes that may help explain why so many chronic diseases are connected, even when they are treated as...
Metabolic Psychiatry in Clinical Practice: Brain Energy, Common Pitfalls, & Precision Nutrition | Dr. Bret Scher, MD | The Metabolic Link Ep. 95
In people with severe depression and cognitive decline, brain glucose metabolism has been shown in some studies to decline measurably. Ketone metabolism, by contrast, appears relatively preserved. That single observation is reshaping how resear...
Inuit Metabolism Revisited: Ketosis, Omega-3s, & the CPT1A Arctic Variant | Dr. Gideon Mailer & Nicola Hale | The Metabolic Link Ep. 94
A gene mutation that reduces ketone production in the fasted state is associated with sudden infant death in modern populations. But in the ancestral context where it evolved alongside an omega-3-rich diet, it may have been part of what kept in...
Understanding Female Metabolism: PCOS, Postpartum, and Menopause | Madison Kackley, PhD | The Metabolic Link
In a 12-week clinical trial at The Ohio State University, every woman with PCOS who completed the intervention experienced a change in her menstrual status. One participant, who had never had a period in her life, began menstruating within a we...
Vagal Nerve Stimulation, TBI, and Brain Health: Rethinking Neurological Care | Dr. Michael Hoffman, MD | The Metabolic Link Ep. 92
A veteran walks into the clinic with a persistent migraine. Four minutes of vagal nerve stimulation later, the migraine is gone. This is not a one-off result. It is what Dr. Michael Hoffman has been observing for over seven years in the VA hosp...
